全文获取类型
收费全文 | 20528篇 |
免费 | 1471篇 |
国内免费 | 203篇 |
专业分类
耳鼻咽喉 | 350篇 |
儿科学 | 359篇 |
妇产科学 | 409篇 |
基础医学 | 2732篇 |
口腔科学 | 511篇 |
临床医学 | 1866篇 |
内科学 | 4245篇 |
皮肤病学 | 587篇 |
神经病学 | 1332篇 |
特种医学 | 1118篇 |
外科学 | 2744篇 |
综合类 | 743篇 |
现状与发展 | 1篇 |
一般理论 | 14篇 |
预防医学 | 1019篇 |
眼科学 | 714篇 |
药学 | 1631篇 |
中国医学 | 164篇 |
肿瘤学 | 1663篇 |
出版年
2023年 | 174篇 |
2022年 | 84篇 |
2021年 | 626篇 |
2020年 | 443篇 |
2019年 | 550篇 |
2018年 | 707篇 |
2017年 | 512篇 |
2016年 | 622篇 |
2015年 | 824篇 |
2014年 | 1008篇 |
2013年 | 1082篇 |
2012年 | 1712篇 |
2011年 | 1659篇 |
2010年 | 936篇 |
2009年 | 840篇 |
2008年 | 1173篇 |
2007年 | 1186篇 |
2006年 | 1126篇 |
2005年 | 1069篇 |
2004年 | 840篇 |
2003年 | 692篇 |
2002年 | 568篇 |
2001年 | 523篇 |
2000年 | 514篇 |
1999年 | 401篇 |
1998年 | 130篇 |
1997年 | 101篇 |
1996年 | 78篇 |
1995年 | 89篇 |
1994年 | 90篇 |
1993年 | 71篇 |
1992年 | 157篇 |
1991年 | 169篇 |
1990年 | 137篇 |
1989年 | 133篇 |
1988年 | 119篇 |
1987年 | 133篇 |
1986年 | 107篇 |
1985年 | 94篇 |
1984年 | 72篇 |
1983年 | 69篇 |
1982年 | 36篇 |
1979年 | 60篇 |
1977年 | 39篇 |
1975年 | 38篇 |
1974年 | 39篇 |
1973年 | 36篇 |
1972年 | 37篇 |
1970年 | 35篇 |
1969年 | 40篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
51.
52.
53.
54.
During the three the coronavirus disease 2019 (COVID-19) surges in South Korea, there was a shortage of hospital beds for COVID-19 patients, and as a result, there were cases of death while waiting for hospitalization. To minimize the risk of death and to allow those confirmed with COVID-19 to safely wait for hospitalization at home, the local government of Gyeonggi-do in South Korea developed a novel home management system (HMS). The HMS team, comprised of doctors and nurses, was organized to operate HMS. HMS provided a two-way channel for the taskforce and patients to monitor the severity of patient''s condition and to provide healthcare counseling as needed. In addition, the HMS team cooperated with a triage/bed assignment team to expedite the response in case of an emergency, and managed a database of severity for real-time monitoring of patients. The HMS became operational for the first time in August 2020, initially managing only 181 patients; it currently manages a total of 3,707 patients. The HMS supplemented the government''s COVID-19 confirmed case management framework by managing patients waiting at home for hospitalization due to lack of hospital and residential treatment center beds. HMS also could contribute a sense of psychological stability in patients and prevented the situation from worsening by efficient management of hospital beds and reduction of workloads on public healthcare centers. To stabilize and improve the management of COVID-19 confirmed cases, governments should organically develop self-treatment and HMS, and implement a decisive division of roles within the local governments. 相似文献
55.
56.
57.
58.
Laura Tapella Teresa Soda Lisa Mapelli Valeria Bortolotto Heather Bondi Federico A. Ruffinatti Giulia Dematteis Alessio Stevano Marianna Dionisi Simone Ummarino Annalisa Di Ruscio Carla Distasi Mariagrazia Grilli Armando A. Genazzani Egidio D'Angelo Francesco Moccia Dmitry Lim 《Glia》2020,68(3):543-560
Astrocytes perform important housekeeping functions in the nervous system including maintenance of adequate neuronal excitability, although the regulatory mechanisms are currently poorly understood. The astrocytic Ca2+/calmodulin-activated phosphatase calcineurin (CaN) is implicated in the development of reactive gliosis and neuroinflammation, but its roles, including the control of neuronal excitability, in healthy brain is unknown. We have generated a mouse line with conditional knockout (KO) of CaN B1 (CaNB1) in glial fibrillary acidic protein-expressing astrocytes (a stroglial c alcin eurin KO [ACN-KO]). Here, we report that postnatal and astrocyte-specific ablation of CaNB1 did not alter normal growth and development as well as adult neurogenesis. Yet, we found that specific deletion of astrocytic CaN selectively impairs intrinsic neuronal excitability in hippocampal CA1 pyramidal neurons and cerebellar granule cells (CGCs). This impairment was associated with a decrease in after hyperpolarization in CGC, while passive properties were unchanged, suggesting impairment of K+ homeostasis. Indeed, blockade of Na+/K+-ATPase (NKA) with ouabain phenocopied the electrophysiological alterations observed in ACN-KO CGCs. In addition, NKA activity was significantly lower in cerebellar and hippocampal lysates and in pure astrocytic cultures from ACN-KO mice. While no changes were found in protein levels, NKA activity was inhibited by the specific CaN inhibitor FK506 in both cerebellar lysates and primary astroglia from control mice, suggesting that CaN directly modulates NKA activity and in this manner controls neuronal excitability. In summary, our data provide formal evidence for the notion that astroglia is fundamental for controlling basic neuronal functions and place CaN center-stage as an astrocytic Ca2+-sensitive switch. 相似文献
59.
Lai Hou Yee Foo Li Lian Lim Siu Min Yong Chen Fei Loh Pui San Chaw Sook Hui Hasan Mohd Shahnaz Wang Chew Yin 《Clinical autonomic research》2020,30(1):53-60
Clinical Autonomic Research - Comparison of hemodynamic profiles and pain scores in diabetic patients undergoing diabetic foot surgery receiving peripheral nerve block (PNB) or spinal anesthesia... 相似文献